How to Make Your Botox More Effective

BOTOX IMPROVES TREATMENTS AND TREATMENTS IMPROVE BOTOX

Botox smooths wrinkles, but for the best, most comprehensive, and natural result paring your Botox Cosmetic treatment with those treatments we offer will improve your results.

Core Science: Botulinum toxin type A blocks acetylcholine release at the neuromuscular junction. This temporarily weakens or paralyzes the targeted facial muscles, reducing the repetitive contractions that cause dynamic wrinkles formed by expression. When muscles relax, the overlying skin smooths out. Younger clients: dynamic wrinkles, meaning they appear when you make expressions. ‘Older’ clients: Both Static (skin damage) and Dynamic: For effective treatments you need to address all the reasons you have less youthful skin. Botox has been used on millions of individuals and the medication is very safe, few contraindications exist beyond a known hypersensitivity, and local infection at site of injection.

Key Studies: 26 Approved Indications for botox Globally, here’s a snapshot of approval timeline

1. 1989: Strabismus, blepharospasm
2. 2004: Axillary hyperhidrosis
3. 2010: Migraines
4. 2011/2013: Detrusor overactivity, OAB
5. 2002: Glabellar lines
6. 2013: Crow’s Feet
7. 2017: Forehead lines (WITH GALBELLAR TREATMENT)
8. 2024: Platysma Bands: Full Correction brings dosing to 100u
9. 2021: Preventive study in women 20-30s with

botox’s effectiveness Beyond Wrinkles is backed by scientific studies, here are a few:

1. Skin Health
   1. Pore size: Neurotoxins can reduce the appearance of enlarged facial pores, particularly in the T-zone. A 2015 study (Park et al., Dermatologic Surgery) found intradermal Botox injections decreased pore size by 20–30% at 8 weeks, likely due to reduced sebaceous gland activity and muscle tension around pores.
   2. Sebum production: In young skin (20s–30s), high sebum output contributes to oily skin and larger pores. In older skin (postmenopause), sebum production typically decreases due to lower estrogen and androgen levels, leading to drier skin. However, neurotoxins can modestly reduce sebum in both age groups. A 2018 randomized trial (Min et al., Journal of Cosmetic Dermatology) showed intradermal Botox reduced sebum production by 20–40% at 4–8 weeks in oily skin patients, with effects lasting 2–3 months. This makes it useful for oily skin in younger patients or for balancing oiliness in some menopausal women with mixed concerns.
2. Facial Balancing
   1. Asymmetries: studied in facia palsy patients, but especially important to improve your look with Botox: let your provider balance you for best Botox Effectiveness
   2. Aesthetic facial contouring: eyebrow lift, gummy smile, downturned mouth (DAO), chin retrusion, lower face descent, masseter for facial slimming
   3. Ultrasound guidance
3. Complementary Treatments
   1. Neurotoxins Botox effectiveness is best when combined with other modalities. Here’s the science behind popular add-ons. Every study out there shows higher patient satisfaction when treatments are combined
   2. Intradermal Hyaluronic Acid+ Botox: Split faced studies: Superior wrinkle reduction, enhanced skin hydration, firmness, texture improvement, elasticity, radiance ‘HYDROTOXDIN’
   3. Chemabrasion: Botox a week before chemabraision produced results that lasted 3 Years!
   4. Chemical Peels (e.g., glycolic, TCA, Jessner’s): Medium-depth peels increase cell turnover, improve texture, reduce fine lines, and fade pigmentation. A 2020 meta-analysis (Lee et al., Dermatologic Surgery) showed moderate-to-significant improvement in photoaging scores when peels were combined with neurotoxins vs. neurotoxins alone. 2024 study of VI peel and Botox on same day showed 60% improvement in wrinkle reduction, 59% pigment uniformity, 70% improvement in skin tone
   5. Microneedling: Creates micro-injuries to stimulate collagen and elastin. A 2022 randomized trial (Alster & Li, Dermatologic Surgery) found microneedling + neurotoxin improved skin texture, pore size, and wrinkle depth more than either alone. Can be applied topically with or without PDGF/PRP
   6. Ultherapy (Microfocused Ultrasound): Tightens skin and stimulates deep collagen. A 2021 study (Fabi et al., Journal of Cosmetic Dermatology) showed Ultherapy + neurotoxin enhanced lifting and wrinkle reduction in the lower face compared to neurotoxin monotherapy.
   7. BBL (BroadBand Light): Targets redness, pigmentation, and collagen stimulation. A 2023 split-face study (Kauvar et al., Lasers in Surgery and Medicine) demonstrated BBL + neurotoxin significantly improved tone, texture, and fine lines versus neurotoxin alone.
   8. Moxi (Gentle Fractional Non-Ablative Laser): Low-downtime laser for texture and tone. Early data (2024 pilot studies) suggest combining Moxi with neurotoxin enhances overall skin smoothness and glow.
   9. Halo (Hybrid Fractional Laser): Combines ablative and non-ablative wavelengths for deeper resurfacing. A 2023 study (Waibel et al., Lasers in Surgery and Medicine) found Halo + neurotoxin produced superior improvement in wrinkles, pores, and pigmentation compared to neurotoxin alone.

The Experts at Hada Cosmetic Medicine would like to develop a plan for your skin radiance. Come for a consult.